The African Center for Translational Genetics (ACTG) is a not-for-profit entity with funding from 54gene Inc as part of its vision to democratize precision medicine. The objectives of the centre are to empower the next generation of African genomic scientists through the provision and implementation of grants, fellowships, and internships; enable better health outcomes by powering the discovery of disease variants which will significantly improve responses to drugs especially among African populations, and enhance therapy on the African continent by enabling individualized and precise care that utilizes patient unique genetic identity to develop new targets to medicine. As part of ACTG’s pillar on strengthening research, two landmark studies aimed at gathering demographic and health information, as well as, genomics data from 100,000 Nigerians in the first instance are being funded under the auspices of the ACTG. This would serve as a veritable pool of resources that would drive the generation of insights that would have the potential of improving knowledge and health outcomes for Africans and other global populations. These studies are being conducted by a team of researchers under the Non-Communicable Diseases Genetic Heritage Study (NCD-GHS) Consortium. The Non-Communicable Diseases – Genetic Heritage Study (NCD-GHS) Consortium is a collaboration between 54gene, Nigerian Institute of Medical Research (NIMR) and the National Biotechnology Development Agency’s Center for Genomics Research and Innovation (NABDA-CGRI).